Attorney Brian White Personal Injury Lawyers | June 9, 2025 | Exsanguination
Exsanguination is a medical term that means severe blood loss, so severe that it can lead to death if not treated quickly. It’s one of the most dangerous injuries a person can suffer, and in many trauma cases, it’s the leading cause of death before a victim ever reaches the hospital.
While it sounds like a technical or rare condition, exsanguination can happen suddenly in everyday accidents. Understanding what it is, how it happens, and why quick action is critical can help save lives.
What Does “Exsanguination” Mean?
The word comes from the Latin prefix “ex,” meaning “out of,” and the Latin word “sanguis,” or “blood.” It literally means “to drain of blood” or “out of blood.” In medical terms, exsanguination refers to the loss of a large amount of blood that is life-threatening and potentially fatal.
Exsanguination usually refers to the loss of more than 40% of the body’s total blood volume. An average adult weighing between 150 and 180 pounds has between 1.2 and 1.5 gallons of blood.
For the typical adult, the loss of two liters (or more than half a gallon) is enough to cause life-threatening exsanguination. Once this level of blood loss occurs, the body can’t maintain normal function. Organs begin to shut down, and death can happen in minutes without emergency care.
What’s the Difference Between Exsanguination and Bleeding?
Not all bleeding is dangerous. A small cut may look dramatic, but it rarely leads to serious blood loss. Exsanguination is different: it involves uncontrolled, large-volume bleeding that overwhelms the body’s ability to cope.
There are two main types of bleeding that can lead to exsanguination:
- External bleeding: You can see the blood, usually from a wound, limb, or open injury.
- Internal bleeding: This occurs inside the body and can be harder to detect. It may happen after blunt trauma or due to a ruptured vessel or organ damage.
Internal bleeding can be especially deadly because it’s harder to spot and treat quickly.
How Does Exsanguination Happen?
Exsanguination is usually caused by a major trauma or injury, particularly pelvic and thoracic injuries.
Some common causes include:
- Car accidents and other high-speed collisions
- Assault, particularly shootings and stabbings, which can damage arteries or vital organs
- Workplace accidents, particularly involving heavy machinery or falls in construction and industrial jobs. These accidents can cause traumatic amputations, deep lacerations, and organ damage.
- Falls from a great height can cause internal bleeding and compound fractures that damage vessels and arteries
- Medical complications during childbirth or surgery. Sometimes these complications are caused by medical malpractice.
- Gastrointestinal (GI) disorders and related complications, such as diverticulosis and esophageal tears
- Aneurysms, which can cause sudden, uncontrolled internal bleeding
- Other medical conditions, such as rare blood disorders
Exsanguination may be caused by an external or internal injury. However, even with visible external trauma, internal bleeding may be a greater and hidden threat.
What Happens During Exsanguination?
When a person starts to lose blood rapidly, their body goes into hemorrhagic shock. There are four classes, which begin with up to 15% blood loss.
Rapid, significant blood loss triggers a dangerous cycle of:
- Core hypothermia: when the core body temperature drops below (95°F)
- Acidosis: reduced blood pH, which causes confusion, fatigue, increased heart rate, and other effects
- Coagulopathy: impaired coagulation (clotting)
- Dysrhythmia: abnormal heartbeat or rhythm
As blood loss increases, heart rate and breathing rate increase rapidly while blood pressure drops. The heart tries to pump faster to keep oxygen flowing to the brain and organs, but without enough blood, this becomes impossible.
As blood pressure drops, the heart, brain, and other organs do not receive the oxygen and nutrients they need. Cells begin to die from a lack of oxygen, and organ failure occurs. This lack of oxygen often results in a brain injury.
Signs of exsanguination include:
- Rapid heartbeat and breathing
- Pale or bluish skin
- Cold, clammy skin
- Weakness or confusion
- Loss of consciousness
- Little or no urine output
Without quick treatment, exsanguination can lead to multi-organ failure and death in less than 10 minutes.
Exsanguination and hemorrhage cause about half of trauma-related deaths. Nearly 60,000 people die from exsanguination in the U.S. every year.
How Is Exsanguination Treated?
Treatment must happen fast. Emergency medical teams often follow a protocol called “Stop the Bleed” which focuses on controlling bleeding right away. This may involve:
- Applying direct pressure to the wound
- Using a tourniquet for limb injuries
- Sealing chest wounds to prevent air loss
- Giving IV fluids or blood transfusions
- Emergency surgery to stop internal bleeding
In trauma care, the first hour after injury is called the “golden hour.” That’s the window where treatment is most likely to save a life. If too much blood is lost too quickly, even the best medical care may not be enough.
Can Exsanguination Be Prevented?
While accidents aren’t always avoidable, quick thinking can make a huge difference. First aid knowledge can help bystanders stop life-threatening bleeding while waiting for help to arrive. Programs like Stop the Bleed, developed by the American College of Surgeons, teach people how to control severe bleeding with hands-on training.
Keeping tourniquets and other emergency first aid supplies in workplaces, vehicles, and public spaces can also save lives in emergencies.
Speak With a Lawyer If Exsanguination Was Caused by Negligence
Exsanguination is a life-threatening emergency, and in many cases, it’s the result of preventable accidents or negligence—whether in a car crash, workplace incident, or medical setting. If you or a loved one has suffered severe blood loss due to someone else’s actions or failure to act, you may have the right to seek compensation for your injuries, medical bills, and more.
At Attorney Brian White Personal Injury Lawyers, we understand the devastating impact of catastrophic injuries like exsanguination. Contact our experienced personal injury attorneys today to discuss your case and protect your legal rights.
Contact a Houston Personal Injury Lawyer to Help You With Your Claim
For more information, contact the Houston personal injury law firm of Attorney Brian White Personal Injury Lawyers by calling (713) 500-5000.
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